Predator arcade was one of the first video games to combine elements from two separate, non-related film franchises into a single game, following 1991's RoboCop Versus The Terminator.

Colonial Marine (Private, Sergeant, Corporal).

Kevin: A Colonial Marine who is a friend of Dutch, he was injured by the Razor Claws.

He has the ambition to control the Xenomorph race so he can turn them into bio-weapons.

General Bush: A Colonial Marine general working for the Weyland-Yutani corporation.

Mad Predator: A Predator infectoid who is the secondary antagonist.

Predator Hunter: A Young Blood Predator.

He lives only to avenge himself against the aliens. He lost his arm in the 2nd Alien War and has since had it replaced with a smartgun rig.

Major Dutch Schaefer: A cyborg created to fight extra-terrestrials.

Lieutenant Linn Kurosawa: A very powerful cyborg with super-human fighting skills who is the leader of the 13th USCM Corps, equipped with a pistol and a katana she is the only survivor of the San Drad Xenomorph infestation alongside Dutch Schaefer.

When asked why the Predators helped, they jokingly light their Plasmacaster sights at them with the leader saying, 'They'll know,' before departing into space, indicating their hunting season is over. The story ends with the veteran Predator (Predator Warrior) breaking off his Wristblade and giving the piece to Linn and Dutch. In the end, the Alien Hive on Earth is destroyed by a military ship set on a course that causes it to crash into San Drad, destroying the Alien threat along with a good portion of the western US, if the explosion in the ending credits is to scale.

Eventually, it is discovered that the Alien presence on Earth (and the subsequent swarm that overran San Drad) was the result of an experiment headed by a United States Colonial Marine Corps general known as Bush in conjunction with the Weyland-Yutani Corporation. The Predators offer an alliance with the humans, in order to stop the Xenomorph infestation.

Before they can be killed, two Yautjas appear and destroy the Xenomorphs, saving the soldiers. Two soldiers were caught in the town during the initial alien outbreak and were abandoned by the rest of their team as well as their superiors, and are cornered by a swarm of Xenomorph Drones. San Drad, California has been overrun by Xenomorphs.

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